During a 26-month period, 6 infants and children were observed with a severe form of pharyngolaryngitis and esophagitis associated with toxic hight fever and severe upper airway obstruction.

• 内视镜检查可发现呼吸道或食道黏膜大量糜烂坏死，同时充满伪膜及脓性黏稠分泌物。