Drugs designed to act on individual molecular targets usually can not combat multigenic diseases such as cancer, or diseases that affect multiple tissues or cell types such as diabetes.

• 作用于单一分子靶标的药物治愈多基因相关疾病如癌症、或影响多个组织或细胞类型的疾病如糖尿病等存在的问题逐渐被人们所认识。