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- First, this term is often used to describe both the viral subtype (A,B,C,D, etc) as well as drug resistance mutations in the HBV DNA polymerase gene. 首先,这个术语经常被用来描述病毒亚型(A,B,C,D等)以及HBV DNA多聚酶基因中出现的耐药性突变。
- The experiences with antiviral therapy for HIV and hepatitis B virus are the caveats for the development of drug resistant mutations. 因此，联合治疗（如：同时使用一种或两种蛋白酶和聚合酶抑制剂）无疑成为了丙肝治疗的规范和标准。
- Another concept is to prevent drug resistance and optimal management of strategy was nucleoside resistance mutation. 而另一种观念是阻止耐药的发生。
- Study on drug resistance mutations among drug-naive HIV-1 carriers in Fujian province 福建省未经抗病毒治疗的HIV-1毒株耐药基因变异研究
- Drug resistance mutations in the protease and reverse transcriptase gene and in the protease substrate cleavage sites of HIV-1 from AIDS pediatric plasma samples 获得性免疫缺陷综合征患儿抗病毒治疗后耐药基因变异分析
- Drug resistance mutations 耐药变异
- Kirby-Bauer was used to detect the drug resistance. 采用kirby -Bauer法检测其耐药性。
- "Looking at [genotypic] mutations over time, we found that this person had a different pattern of mutations associated with drug resistance. 因为我们对其变种基因作长期观察后发现，这位患者所显示出的抗药性型态，与之前是不同的。
- Nucleoside analogues are currently the main drug therapy against HBV infection.However, this type of therapy can cause gene mutations in HBV that result in drug resistance. 核苷类药物是目前抗乙型肝炎病毒(HBV)的主要药物,但它可引起HBV基因的变异,从而引起耐药。
- K562/ADM had no drug resistance to As2O3 and matrine. 非细胞毒性剂量的三氧化二砷和苦参碱均可部分逆转有多药耐药表型的细胞株K562/ADM对阿霉素的耐药J险，二者联合应用效果优于单独应用，具有协同作用。
- Such misuse of medicines can lead to drug resistance. 这样滥用药物会导致抗药性。
- To develop effective combination of drug resistance modulators. 目的:寻找有效的多药耐药联合逆转剂。
- She explained how plasma and breast milk were collected from the 33 women in the trial at 2, 8, 16, and 20 weeks.Both were assayed for viral load and resistance mutations to NVP. 解释如何收集33名妇女的血浆和母乳（收集时间在试验的第2, 8, 16, 和20周）与分析病毒量和对NVP的限制性突变。
- There are many mutations leading to drug resistance exist in the viral genome which varies in different individuals especially in those receiving different anti-viral drugs. 不同乙肝病人在接受不同程度的抗病毒药物治疗后,病毒会出现各式各样的变异,导致病毒基因组产生抗药性。
- Study limitations include insufficient power to detect a change in fungal ecology, short duration, and inability to detect shifts in candida species or the establishment of acquired resistance mutations. 研究的局限性包括：不足的效力来检测真菌的生态学变化，持续时间短、无法检测移入的念珠菌的类型或者建立耐药的变异菌株。
- Drug resistance surveillance of pulmonary tuberculosis in Jiaxing City. 嘉兴市肺结核病耐药监测。
- Study on infections and drug resistance of mycoplasma in female vaginalis. 株解脲支原体耐药分析。
- And similar to penicillin, many bacteria also have had a sulfa drug resistance. 和青霉素类似，很多细菌也对磺胺产生了耐药性。
- IFN combined with ATRA can partially revert drug resistance in MR2 cell. 2：IFN 联合ATRA能够部分逆转MR2细胞耐药。
- Drug resistance is the main restriction factor for clinical usage of taxanes. 耐药是影响紫杉类药物临床疗效的重要因素。
