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- Drug dissolution rate 药物溶出度
- Abstract: Objective: To improve the dissolution rate of a poorly watersoluble drug, tanshinone. 摘 要: 目的:提高难溶性药物丹参酮的体外溶出度。
- The folubility and the dissolution rate were measured. 测定固体分散体溶解度,溶出速率。
- Objective: To improve the dissolution rate of nifedipin tablets in vitro. 目的:提高硝苯地平片的体外溶出速率。
- Conclusion The nifedipine-PEG solid dispersion could accelerate the in vitro drug dissolution. 结论 硝苯地平PEG固体分散体能加快药物的体外溶出速率。
- Conclusion The etodolac-PEG solid dispersion could enhance the drug dissolution in vitro. 结论 依托度酸PEG固体分散体能提高药物的体外溶出度。
- RESULTS: The results of in vitro dissolubility test showed that the higher the carrier- car ratio,the faster the drug dissolution. 结果:载体比例越大,药物溶出愈快;载体比例愈小,差异愈显著。
- Methods To improve the dissolution rate of Mosapride Citrate(MC)by whetting with lactose. 方法采用枸橼酸莫沙必利与乳糖研磨的方法提高其溶出速率。
- AIM Preparing the solid dispersion of anethole trithione so as to increase its solubility and dissolution rate. 目的制备茴三硫固体分散体,提高其溶解度和溶出速率。
- Objective To establish the assay method of dissolution rate on Acipimox Capsules. 目的确立阿昔莫司胶囊溶出度测定方法。
- The model characterizes many dynamic transport and complexation processes that include radial diffusion, excipient complexation and crystalline drug dissolution. 模型利用径向扩散,辅料络合作用和晶体药物的溶出度来表征多个动力学运输和络合过程。
- Result: The dissolution rate of the croscarmellose sodium capsule was accelerated significantly. 结果:交联羧甲基纤维素钠能显著增加萘普生胶囊的溶出速率。
- OBJECTIVE To prepare etoposide solid dispersion to enhance the dissolution rate. 目的制备依托泊苷固体分散体,改善依托泊苷的溶出度。
- RESULTS:The dissolution rate and flexibility of the ophthalmic film could be improved by adding gum bletilla into PVA. 结果:在PVA膜质中加入白芨胶可以改进PVA膜的药物缓释性能及膜的柔软性。
- Objective:To compare dissolution rate of first-researching and imitating Ebastine tablets in vitro. 目的:比较原研和仿制药厂生产的依巴斯汀片的体外溶出度特性。
- Objective To compare the dissolution rates of Pioglitazone Hydrochloride tablets preparation from 3 manufactures and to provide references for rational clinical drug use. 目的比较3个厂家吡格列酮片的溶出度,为临床用药提供参考。
- Objective To study the behavior of Phentolamine Mesylate Tablets in vitro, and determinate the condition of its dissolution rate. 目的考察甲磺酸酚妥拉明片的体外释放行为,制订合理的溶出度测定条件。
- Conclusion The Amoxycillin dispersible tablet made by the four different adjuvants can rapidly disintegrate with a high dissolution rate. 结论经4种不同辅料制备的阿莫西林分散片崩解迅速,溶出度高;
- The results show that the dissolution rate of various minerals in the slag decrease in the following order of spinel, diopside and perovskite. 结果表明:高炉渣中镁铝尖晶石最先浸出,其次是攀钛透辉石和富钛透辉石,钙钛矿的浸出速度最慢。
- Cyclodextrin inclusion technique can remarkably improve the solubility of itraconazole in water and the dissolution rate of itraconazole in vitro. 体外溶出结果表明,固体分散物能显著提高药物在人工胃液中的溶出度。