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- Dopamine receptor site 多巴胺受体部位
- Objective: To detect the genetic association between chronic tic disorder( CTD) and the polymorphism in the dopamine receptor D5 gene. 目的研究慢性抽动障碍与多巴胺D5受体基因多态性是否相关联。
- Clinical treatment of PD includes dopamine replacement such as L-DOPA and D_2 dopamine receptor agonist. 目前临床仍以替代治疗为主,左旋多巴和D_2受体激动剂能改善PD症状,但不能阻制疾病发展,这使人们对PD治疗的认识由单纯替代疗法逐渐转向保护中脑DA能神经元。
- Rotigotine is a non-ergolinic dopamine receptor agonist available as a patch for once-daily use. 罗替戈汀是现有非二氢麦角碱多巴胺受体激动剂中可作为每日一次使用的辅助药物。
- This article reviews the important roles of dopamine receptor in sodium reabsorption and blood pressure. 现就多巴胺受体在调节机体血压和肾脏利钠、利尿作用中所发挥的重要作用作一综述。
- Rotigotine is a non-ergolinic dopamine receptor agonist aailable as a patch for once-daily use. 罗替戈汀是现有非二氢麦角碱多巴胺受体激动剂中可作为每日一次使用的辅助药物。
- A noncompetitive antagonist prevents the agonist from producing any effect at a given receptor site. 非竞争性拮抗剂可阻止激动剂在特定受体部位产生任何效应。
- Background Ergot-derived dopamine receptor agonists, often used in the treatment of Parkinson's disease, have been associated with an increased risk of valvular heart disease. 背景:有发现表明常用于治疗帕金森病的麦角洐生的多巴胺受体激动剂可增加发生瓣膜性心脏病的风险。
- Sodium ions have been shown to play an important role in the binding of antipsychotic drugs to the D2 Dopamine receptor. 钠离子在将D2多巴胺受体融入抗精神病药物合成的过程中扮演着极其重要的角色。
- Researchers found that risk takers have less of a particular type of dopamine receptor, thus they feel happier than normal people when seeking novelty. 研究者发现,冒险者的大脑中没有足够的多巴胺"接收器"来存多巴胺,因此,冒险爱好者每次追求刺激时都会尝到比一般人更大的快感。
- Both classes of drugs are dopamine receptor antagonists that work by blocking the action of naturally occurring dopamine in the brain. 两类药物都多巴胺受体拮抗剂,通过阻断大脑自然发生的多巴胺活性发挥效用。
- A medicine used to treat allergies and hypersensitive reactions and colds,works by counteracting the effects of histamine on the receptor site known as H1. 用来治疗敏感症、敏感反映和伤风的药物,通过和H1受点部位组胺作用相中和而起作用。
- Background Ergot-deried dopamine receptor agonists, often used in the treatment of Parkinson's disease, hae been associated with an increased risk of alular heart disease. 背景:有发现表明常用于治疗帕金森病的麦角洐生的多巴胺受体激动剂可增加发生瓣膜性心脏病的风险。
- The target receptor of psychoactive substance is opioid receptor and the non-target receptor mainly includes dopamine receptor, NMDA receptor, histamine receptor, and so on. 精神活性物质作用的靶受体为阿片受体,非靶受体主要包括多巴胺受体、N-甲基-D-门冬氨酸(NMDA)受体和组胺等。
- Objective To observe the effects of nucleus accumbens lesion in Methamphetamine (MAP) rats on behavior and the expression of Dopamine Receptor D_2 (DRD_2) in special areas of brain through stereotactic technique. 目的探讨立体定向伏隔核毁损对甲基苯丙胺(MAP)模型大鼠行为学及不同脑区多巴胺D2受体表达的影响。
- Results:A microinjection of dopamine or apomorphinc, a dopamine receptor agonist, resulted in an evident increase in blood pressure and heart rate, but haloperidol (halo) can reduced them mildly. 注射多巴胺受体拮抗剂氟哌啶醇则引起血压和心率的降低。
- There are many chemical and environmental toxins that can mimic estrogens and attach to the receptor sites also. 有许多化学和环境毒素,能模仿雌激素和附着到受体网站也。
- The release of neurotransmitter molecules from one neuron and their attachment to receptor sites on another keep a nerve impulse moving. 神经递质分子从一个神经原释放后,附着到另一个接受点,令神经冲动保持运动的状态。
- Isolated blood ring assays were used to study the changes of dopamine receptors in rat aorta vascular smooth muscles after oral L dopa. 采用离体血管环的方法对长期服用非亚型特异性拟多巴胺类药物左旋多巴后大鼠主动脉平滑肌中多巴胺受体两亚型(DA1,DA2)的变化进行了观察。
- Endogenous substance receptor site 内生物质受体部位