Disfunction of lysosomes is the earliest change observed in AD patients, and thought to be caused by oxidative damage induced by A .

• 在阿兹海默症的早期可以发现溶小体有一些不正常的改变，贝他类淀粉蛋白也会对阿兹海默症患者产生一些氧化压力的伤害。