Discussions that led to the accord began after an unlicensed chemical plant in China made a tainted drug ingredient that poisoned more than 170 people in Panama, killing at least 115.

• 中国没有许可证的化学工厂生产受污染的药品配料导致巴拿马170人中毒，至少115人死亡的事件。这件事发生后，开始了这个协议的谈判。