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- Objective To study the expression of three Homer 1 subtypes in diffuse brain injury (DBI) of rats in vitro. 目的研究大鼠弥漫性脑损伤后Homer1蛋白3种亚型表达规律及其意义。
- AIM To set up a new animal model to study the diffuse brain injury (DBI) with secondary brain insult (SBI) in rats. 目的 建立弥漫性脑损伤 (diffusebraininjury ;DBI)合并二次脑损伤 (secondarybraininsult;SBI)大鼠模型 .
- AIM: To study the expression and significance of Homer in diffuse brain injury(DBI)of rat in vitro. 目的研究大鼠弥漫性脑损伤后不同亚型Homer蛋白表达规律及其意义.
- The experimental study of expression of vascular endothelial growth actor in diffuse brain injury. 大鼠弥漫性脑损伤中血管内皮生长因子表达变化的实验研究
- RD-5 mRNA expression in rat intestines increased significantly after diffuse brain injury at 24 hours(P<0.01),and at 3 days it was decreased to a level lower than control. 弥漫性脑损伤后24hRD-5mRNA的表达显著升高(P<0.;01);伤后3d降低至正常水平以下。
- CONCLUSION In the development of diffuse brain injury with SBI, mGluR3 may play an important role in protecting brain, and its agonist DCG IV can availably alleviate the degree of brain injury. 形态学研究证实 ;DCG- IV干预能明显减轻脑皮层神经元损伤程度 .;结论 在弥漫性脑损伤和 SBI所致的脑损害发生与发展过程中;m Glu R3的作用可能与脑保护有关;其激动剂 DCG- IV能有效降低脑组织损伤程度
- Objective To investigate the neuroprotective mechanism of taurine(Tau)by observation of the effects Tau on the cognitive function and the expression of Bcl-2 and Bax at hippocampus after diffuse brain injury(DBI) in rats. 目的观察牛磺酸(Tau)对弥漫性颅脑损伤大鼠学习记忆和海马Bcl-2和Bax蛋白表达的影响,探讨其神经保护作用机制。
- Diffuse brain injury (DBI) is the most common TBI. Epidemiological investigation shows DBI comprises 73% of the total serious brain injuries in road accidents. 弥漫性脑损伤(Diffuse brain injury,DBI)在TBI中占有重要地位,流行病学调查显示DBI占交通伤后重型脑创伤的73%25。
- AIM To study the changes and effects of metabotropic glutamate receptor subtype 2 (mGluR2) in diffuse brain injuries (DBI) coupled with secondary brain insults (SBI) in rats. 目的 研究弥漫性脑损伤 (diffusebraininjury;DBI)及其合并二次脑损伤 (secondarybraininsults;SBI)后大鼠脑皮层代谢性谷氨酸受体 2亚型 (mGluR2 )的变化及其意义 .
- AIM To study the changes and effects of metabotropic glutamate receptor subtype 4 (mGluR4) after diffuse brain injuries (DBI) coupled with secondary brain insults (SBI) in rats. 目的 研究弥漫性脑损伤 (DBI)及其合并二次脑损伤 (SBI)后大鼠脑皮层代谢型谷氨酸受体亚型 4(m Glu R4)的变化及意义 .
- MCPG protects brain tissues after diffuse brain injury in rats 代谢型谷氨酸受体拮抗剂MCPG对大鼠弥漫性脑损伤的保护作用
- Keywords Homer;immunoblotting;diffuse brain injury;rats; 免疫印迹法;弥漫性脑损伤;大鼠;
- Aim To observe the effects of insulin like growth factor 1(IGF 1) on neuronal loss in the cerebral cortex following diffuse brain injuries(DBI) in rats and investigate the possibility of IGF 1 in treating the brain injuries. 目的观察胰岛素样生长因子-1(insulin-likegrowthfactor-1,IGF-1)对大鼠弥漫性脑损伤(diffusebraininjury,DBI)皮层神经元死亡的影响,探讨应用IGF-1治疗脑损伤的可行性。
- Expression of Homer after diffuse brain injury in rats and its significance 大鼠弥漫性脑损伤后Homer蛋白的表达及其意义
- Expression and significance of Homer1a, 1b/c after diffuse brain injury in rats 大鼠弥漫性脑损伤后Homer1a及1b/c蛋白表达及意义
- Keywords Diffuse brain injury;Dorsal vagal complex;Visceral motility;Neurons; 颅脑损伤;背侧迷走神经复合体;内脏活动;神经元;
- Keywords synaptophysin;diffuse brain injury;post injury time interval; 突触体素;弥漫性脑损伤;损伤时间;
- Window of opportunity for treatment with insulin-like growth factor-1 after diffuse brain injury in rats 大鼠弥漫性脑损伤后胰岛素样生长因子-1的治疗时间窗研究
- The research of neuro protection effect of scopolamine hydrobromide on diffuse brain injury in rats 东莨菪碱对大鼠弥漫性脑损伤的脑保护作用研究
- Protective effect of insulin- like growth factor- 1 in rats with diffuse brain injury 胰岛素样生长因子-1对大鼠弥漫性脑损伤的保护