Diazaspiro [4.4] nonane was synthesized from malononitrile as the starting material by a series of nucleleophilic displacement, hydrolytic cyclization and carbonyl reduction.

• 摘要以丙二腈为原料，经过亲核取代、水解环合、羰基还原系列反应，合成了2，7-二氮螺[4.；4]壬烷。