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- Dextromethorphan Hvdrochloride 盐酸美沙芬, 盐酸右甲吗喃[镇咳药]
- Dextromethorphan hydrobromide and ibuprofen capsules were determined by HPLC. 用HPLC测定复方胶囊中右美沙芬、布洛芬的溶出度。
- It is practicable to apply the method for the assay of Dextromethorphan Hydrobromide and Guaifenesin for Suspension. 结论：方法准确、灵敏、可靠,适用于氢溴酸右美沙芬愈创甘油醚干混悬剂的含量测定。
- Dextromethorphan hydrobromide sustained-release matrix pellets wereproduced by extrusion-spheronisaion. 氢溴酸右美沙芬骨架缓释微丸的制备采用挤出滚圆法。
- Objective To evaluate the stability of the controlled-release pellets of dextromethorphan hydrobromide. 目的考察氢溴酸右美沙芬控释胶囊的稳定性。
- Objective: To prepare the dextromethorphan oral sustained-release suspensions and study the in-vitro release kinetics. 目的:制备右美沙芬树脂口服缓释混悬液,并考察其释药特性。
- HPLC method for determination of guaifenesin and dextromethorphan hydrobromide in dispersibletablets was established. 建立了HPLC法测定愈美分散片中愈创木酚甘油醚和氢溴酸右美沙芬的含量。
- Conclusion: Dextromethorphan has synergism to Methadone and reduce its dosage during detoxification. 结论美沙芬对美沙酮有协同作用,可以减少脱毒治疗时美沙酮的用量。。
- Objectives: To examine the effect of dextromethorphan in the treatment of heroin withdrawal symptoms by Methadone. 目的研究美沙芬在美沙酮治疗海洛因戒断症状中的作用。
- Methods Dextromethorphan Sustained-Release capsules of lasting antitussive were observed by acid citric induced cough model of guinea pig. 目的观察氢溴酸右美沙芬缓释胶囊的镇咳作用及镇咳作用时间。
- Objective:To research the preparation, control in quality and stability of Paracetamol pseadoephedrine Hydrochloride and Dextromethorphan Hydrobromide dispersible tablet. 目的:研究氨芬伪麻美芬片的制备并对其质量进行控制和稳定性考察。
- Dextromethorphan is a synthetic compound.Dextromethorphan has been abused and is claimed to be habit forming but has not been reported to produce physical dependence. 氢溴酸右美沙芬和其代谢物右啡烷的止咳作用主要是由于与中央神经系统的非鸦片样药感受器官结合。
- Here the measurement of 50% inhibitory concentration (IC50) for CYP2D6 with non-inhibitor (dextromethorphan) and inhibitor (quinidine) using SPR biosensor is demonstrated. 因此在此以CYP2D6为例，测量50%25抑制浓度来比较非抑制性药物和抑制性药物的差别。
- Method: A randomized, single-hlind and controlled study was carried out, dextromethorphan plus Methadone were applied in study group (N=25) and only Methadone in control group. 方法采用随机单盲对照试验设计,试验组25例采用美沙芬与美沙酮合并用药,对照组25例仅用美沙酮。
- Methods:Using orthogonal designed compound dextromethorphan syrup as a model drug.The grade point synthesized was introduced to quantify the stability characteristics. 方法:以复方氢溴酸右美沙芬糖浆为模型药物,采用正交设计,在评价指标中引入综合评分来量化稳定性和口感,考察不同处方、工艺对此指标的影响程度。
- Their duration of action was longer than that of lidocaine.Co-administration of dextromethorphan and its metabolites produced additive effect on sciatic nerve blockade. 而且当右美沙芬、右啡烷、甲氧基吗啡喃与利多卡因合并给予在大白鼠周边的坐骨神经阻断上亦具有加成作用。
- HPLC method with fluorescence detection for determination of dextromethorphan (1) and its active metabolite, dextrorphan (2) in human plasma was presented. 建立了简便、准确、灵敏的反相高效液相色谱-荧光检测法测定人血浆中右美沙芬和活性代谢物去甲右美沙芬的血药浓度。
- OBJECTIVE: To establish a LC/MS method for the determination of dextromethorphan in human plasma and to study its pharmacokinetics in healthy Chinese volunteers. 目的:建立以液/质联用法测定人血浆中右美沙芬浓度的方法,并研究其在健康人体的药动学。
- Methods:The dextromethorphan oral sustained-release suspensions were prepared using ion exchange resin as a carrier,and followed by coating with ethylcellulose using the Wurster fluid bed process. 方法:采用离子交换树脂为载体制备含药树脂微粒,用流化床进行包衣,并通过处方优化制备右美沙芬树脂口服缓释混悬液。
- The bioequivalence and pharmacokinetics of domestic dextromethorphan hydrobromide extended release suspension was investigated in 18 healthy man volunteers, according to randomized crossover design. 在18名男性健康受试者中研究国产右美沙芬缓释混悬液的药物动力学特性及生物等效性。
