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- Demotina atran. 黑茶肖叶甲
- ATRA and/or NaB both stimulated p21 expr ession at the mRNA levels. ATRA和 (或 )NaB均上调P2 1mRNA的水平。
- Objective To prepare and optimize formulation of ATRA liposomes. 目的通过制备不同配方全反式维甲酸脂质体,对处方进行优化。
- To study the growt h in-hibitory effects of 8-MOP or/ahd ATRA on Mc3cells. 研究8-MOP与ATRA单独及联合应用对Mc3细胞的生长抑制作用。
- IFN combined with ATRA can partially revert drug resistance in MR2 cell. 2：IFN 联合ATRA能够部分逆转MR2细胞耐药。
- OBJECTIVE To purify cytotoxin(CTX) from Naja naja atra venom,and to study its antitumor activity. 目的分离纯化眼镜蛇毒细胞毒素,测定其体内外抗癌作用。
- METHODS CTX-d was fractionated and purified from Naja naja atra venom by column chromatography and RP-HPLC. 方法应用柱层析及RP-HPLC,从眼镜蛇毒粗毒中分离纯化细胞素素(CTX)。
- Objective:To detect the mechanism of hyperleukocytosis in patients with APL after treatment with ATRA. 目的 :揭示 APL患者 ATRA治疗后高白细胞征的机制。
- Objective:To investigate the effect of ATRA on the apoptosis in HL 60 cells induced by Ara C. 目的 :探讨 HL- 6 0细胞经全反式维甲酸 (ATRA)作用后对化疗药物阿糖胞苷 (Ara- C)诱导凋亡敏感性的变化。
- Conclusions Apoptosis in the AsGnT-V/SMMC-7721 cells induced by ATRA are related to ER stress. 结果GRP78和XBP1的变化表明经ATRA处理后AsGnT-V/SMMC-7721细胞的内质网应激加剧了,而与内质网应激相关的凋亡分子CHOP、caspase-9、caspase-12以及caspase-3都发生了激活。
- The As 2O 3 and ATRA in the treatment of APL can obtain a higher CR rate and a shorter duration for achieving CR. ATRA联合As2 O3 治疗APL患者不仅能获得好的疗效 ,而且能缩短达CR的时间。
- Methods An apoptotic cell model of MCF 7 cells was constructed with ATRA induction. 方法 用全反式维甲酸诱导人乳腺癌MCF 7细胞凋亡 ,建立肿瘤细胞凋亡模型 ;
- Methods Twenty APL patients were treated with the ATRA and As 2O 3 combination, and 18 of them could be evaluated. 方法 As2 O3 联合ATRA治疗初治和复发APL患者 2 0例 (可评价的患者 18例 )。
- Methods:All the17patients with APL were treated by ATRA plus chemotherapy after complete remission(CR). 方法:对17例经ATRA治疗取得完全缓解(CR)的APL患者,采用ATRA与化疗交替方案进行治疗。
- Different concentrations of ATRA have different effects on morphology, proliferation and apoptosis of the RPE cells. 不同浓度的ATRA对RPE细胞的形态、增殖有不同的影响。
- The TM transcription and expression upregulated by ATRA may alleviate dysfunction of coagulation in APL. ATRA增高TM转录及表达,缓解APL患者凝血功能异常。
- Conclusion There are significant improvement in prognosis of APL treated with ATRA. 结论全反式维甲酸对急性早幼粒细胞性白血病患者的预后有很大改善。
- In vitro, Tamibarotene is approximately 10 times more potent than ATRA at causing APL cells to differentiate and die. 该药物显示对ATRA缓解后复发的APL具有显著有效性，对ATRA应答困难患者的有效性也可期待。
- Objective To determine the effect of all-trans retinoic acid (ATRA) on human tongue carcinoma. 目的研究维甲酸对舌癌细胞株的诱导分化作用。
- Patients with M3 who use the ATRA have the higher CR rate(91%) than those who have the single chemotherapy(25%). M_3患者应用全反式维甲酸(ATRA)后CR率(91%25)明显高于单用化疗者的CR率(25%25)。
