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- Mongolian gerbils were used as delayed neuronal damage (DND) animal models. 本文用蒙古沙土鼠制作迟发性神经元损伤(DND)动物模型。
- Mongolian gerbil was used as the delayed neuronal damage (DND)animal model, and was submitted to 5-minute cerebral ischemia by bilateral carotid artery occlusion, followed by 1 to 96 hours reperfusion. 本文以结扎沙土鼠双侧项总动脉5min,然后使血流再通的方法制作迟发性神经元损伤动物模型。
- Delayed neuronal damage 迟发性脑损伤
- BackgroundCerebral ischemia reperfusion damage is a kind of delayed neuronal death ( DND). A lot of investigations have showed that DND is closely related to apoptosis. 脑缺血再灌注损伤是一种迟发性神经元死亡(delayed neuronal death,DND)，大量研究表明DND与细胞凋亡(cell apoptosis,CA)密切相关。
- NGF could ease the delayed neuron death (DND) after ischemia reperfusion. NGF可以减轻海马迟发性神经细胞死亡 (DND)性损伤。
- MDMA targets the serotonergic system and can cause serotonin neuronal damage. MDMA主要作用于5-羟色胺能系统,并能引起5-羟色胺神经元损伤。
- Transient cerebral ischemia may result in degeneration, necrosis, delayed neuron death( DND) and/ or apoptosis. 短暂性脑缺血可出现神经元变性、坏死、迟发性神经元死亡和/凋亡。
- In conclusion,C fos activation after cerebral ischemia may have regulated the delayed neuronal death in the CA 1 region of hippocampus. 脑缺血诱导的c－fos基因表达对于缺血易损海马CA1区迟发性神经元坏死可能起直接的调控作用。
- Transient cerebral ischemia may result in degeneration, necrosis, delayed neuron death ( DND) and/or apoptosis. 短暂性脑缺血可出现神经元变性、坏死、迟发性神经元死亡和/或凋亡。
- Transient cerebral ischemia may result in degeneration, necrosis, delayed neuron death( DND) and/ or apoptosis . 短暂性脑缺血可出现神经元变性、坏死、迟发性神经元死亡和/凋亡。
- Objective To investigate the role of nitric oxide (NO) in neuronal damage in the rat model of Parkinson ,s disease (PD). 目的 研究一氧化氮 (NO)在帕金森病 (PD)大鼠模型神经损伤中的作用。
- The serum preparation of CSC (2,4,8g/kg) attenuated neuronal damage during hypoxia 3 h / reoxygenation (0,3,6,18 h) by decreasing LDH release. 其含药血清可抑制缺糖 缺氧3h再灌 0h、3h、6h和 1 8h引起的神经细胞内LDH的释放。
- Ischemia for 6 min resulted in a apparent delayed neuron death (DND) in the hippocampus, while ischemia for 3 min did not cause DND in the hippocampus. 缺血 6min即可导致海马组织明显的神经元延迟性死亡 (delayedneurondeath ,DND) ,而缺血 3min不足以引起海马组织明显的DND。
- MDMA abuse commonly occurs in combination with ethanol,and ethanol can increase hydroxyl radicals formation and serotonin neuronal damage. MDMA常和乙醇合并滥用。乙醇可促使羟基自由基增多,并使5-羟色胺神经元损伤加重。
- Ischemia for 6 min resulted in an apparent delayed neuron death (DND) in the hippocampus, while ischemia for 3 min did not cause DND. 发现缺血 6min即可导致海马组织明显的神经元延迟性死亡 (de layedneurondeath ,DND) ,缺血 3min不足以引起海马组织明显的DND ;
- Objective To explore the level of serum neuron-specific enolase(s-NSE) and brain neuronal damage in the migraine patients during attack. 目的探讨偏头痛发作期患者血清神经元特异性烯醇化酶(S-NSE)水平及其对脑神经元的损伤。
- Conclusion Piper kadsura Ohwi may play protective effects by reducing necrosis and delayed neuronal cell death after focal cerebral ischemia in aged rats. 结论海风藤具有抵御缺血后血脑屏障破坏，减少缺血灶周围神经细胞坏死及迟发性神经元死亡．发挥缺血性脑保护作用。
- MT-1,-2 KO mice exhibited greater neuronal damage after permanent middle cerebral artery occlusion (MCAO) than wild-type mice. MT-1型和-2型可以防止活性氧和自由基损伤。我们通过MT-1,-2 基因敲除的小鼠来研究金属硫蛋白-1 , -2的作用。
- Since the concept of delayed neuron death (DND)was first brought up at 1982,it is one of the hot spots in which the researchers are interested. 迟发性神经元死亡(DND)自1982年被首次提出以来,始终是研究者关注的热点。
- Objective: To observe neuronal damage degree in the fetal mice brains, which caused by undergoing hypoxia at the mid or late of the maternal mice. 目的:观察中、晚期妊娠小白鼠置于低氧环境中不同时间后对其胎鼠脑组织损伤的程度。
