Damage of optic nerve is a clincial common disease.It is helpful to establish reliable stable animal models in reseach of pathomechanism and drug treatment for this type of disease.

• 摘要视神经损伤是临床常见症，建立可靠，稳定的视神经损伤动物模型对研究该病病理机制及药物治疗非常有意义。