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- As leucine zipper is a basic DNA binding motif of many known transcription factors, we examined the transcriptional function of the TCP10L using dual luciferase assay system. 本研究的结果进一步加深了对人体MT基因结构与功能的认识，也为阐明HCC发生的分子机制提供了有重要价值的资料。
- In the context of identifying DNA binding motifs, using inferred transcription rates leads to more significant findings than those based on transcript amounts. 我们发现,对于共调控基因,比较直接用转录产物量,运用转录率可以提高它们的相关性。
- DNA binding motif DNA结合基序
- SRY represents a transcription factor belonging to the superfamily of genes sharing the HMG-box motif (high-mobility group-box), which acts as DNA binding region. SRY基因是一种转录因子，属于带有高迁移率族蛋白家族，该家族成员的包含能与DNA结合的HMG盒基序。
- It encodes a BTB/POZ domain at the N-terminus and a PCNA binding motif (QTKV-EFP) at the C-terminus. 该蛋白的N端具有一个BTB/POZ结合域和C端具有一个PCNA的保守结合域(QTKV-EFP)。
- The structure and expression pattern implies it migh t be a DNA binding transcription regulator. 它的结构和表达特征预示着它编码的是一个具DNA结合功能的转录调控因子.
- EMSA showed that stimulation of HSC by Aldo markedly increased AP-1 DNA binding activity. Aldo可增强HSC的AP-1的DNA结合活性。
- The autoimmune regulator(AIRE) showned DNA binding activity and transcrip-tional transactivation potential. 自身免疫调节因子(autoimmune regulator,AIRE)是一种具有转录活化潜能的DNA结合蛋白。
- There were DNA binding proteins in the SR of rats, and the molecular weight was 78 000 and 60 000 dalton. 大鼠膈肌SR上存在非序列依赖性DNA结合蛋白 ,相对分子质量分别为 6 0 0 0 0道尔顿和 780 0 0道尔顿。
- These oligonucleotides contain consensus DNA binding sites for individual sequence-specific transcription factors. 这些寡核苷酸共同学列是单个序列特异性的转录因子DNA结合位点。
- The autoimmune regulator (AIRE) showned DNA binding activity and transcriptional transactivation potential. 自身免疫调节因子(autoimmune regulator, AIRE)是一种具有转录活化潜能的DNA结合蛋白。
- DNA binding activity of transduction factor and transcription activator 3 between the two groups was similar ?P > 0.05?. 两组之间转导子和转录激活子3DNA结合活性接近(P>0.;05)。
- Telomeric proteins is composed of double DNA binding protein, single DNA binding protein and telomeric associated proteins. 端粒结合蛋白直接保护端粒DNA,端粒相关蛋白通过与端粒结合蛋白的相互作用间接影响端粒的功能。
- All the results indicated that the structures of amino acid bridge in the ligands may affect the DNA binding and cleavage ability. 研究结果表明氨基酸桥对于配体的DNA键合及裂解能力的有不同影响。
- transcription factor binding motif 转录因子结合模体
- Besides the TATA box and CAAT box, several transcription binding motifs related to stress responses, such as GC motif, EIRE, MRE, WUN motif, ABRE and HSE, were found in the promoter. 除了TATA box和CAAT box以外 ,在AcBADH启动子区还发现了一些与胁迫有关的其它元件 ,如GC motif、EIRE、MRE、WUN motif、ABRE和HSE。
- QCM is a simple, rapid and real-time measurement of DNA binding and hybridization at the sub-nanogram level, so it is applied widely in gene diagnostic, becoming the best of all effective means at molecule biology and microchemistry. 石英晶体微天平(QCM)技术具有简单、快速、灵敏、在纳克级水平上实时检测DNA固定和杂交等优点，被广泛应用于基因学、诊断学等各方面，成为分子生物学和微量化学领域最有效的手段之一。
- The AR protein is composed of four domains,the N-terminal domain(NTD)or transactivation domain,the DNA binding domain(DBD),the flexible hinge region and the ligand binding domain(LBD). AR的配体,雄激素是主要的内源性性类固醇激素,而更多的研究却表明雄激素在鱼类性分化过程中不起作用,AR在此过程中的作用尚不清楚。
- DOC-2 has a phosphotyrosine interactingdomain (PID) on in its N-terminus and multiple proline-rich SH3 binding motifs in its C- terminus. 在其氨基端含有磷酸酪氨酸作用结构域(phosphotyrosine interactingdomain，PID/PTB domain)，羧基端含有多个富含脯氨酸的SH3结合区。
- The 125I labelled anti-ds DNA (125I DNA binding test) was determined in 300 healthy persons, 164 cases of connective tissue disease (CTD) and 59 cases of non-CTD by radio-immunoassay. 本文应用同位素~(125)I标记的抗ds-DNA抗体放射免疫检测300名正常人,164例结缔组织性疾病和53例非结缔组织性疾病的结果。
