DNA hypomethylation,likely to be cooperating with aberrant histone modification,may induce the activation of some T cell genes and development of autoimmunity in SLE.

 
  • DNA的低甲基化可能在异常组蛋白修饰的协同下引起某些T细胞基因的异常活化,导致狼疮自身免疫的发生。
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