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- Conclusion Memantine will affect liver and brain of neonatal rats. 结论美金胺对新生大鼠的脑和肝脏影响较大。
- Of the 44 patients, 50% also received adjunctive therapy with memantine. 其中50%25也接受美金刚的辅助治疗。
- The researchers also found that memantine was able to dampen brain activity in some affected areas and reduce pain accordingly. 研究人员也发现美金刚胺能够抑制脑中受侵袭部位的活动从而减少疼痛。
- The pathologic changes and mortality rate of neonatal rats were positively correlated with the dosage of memantine. 新生大鼠的病理变化程度及死亡率与美金胺的剂量呈正相关。
- To test this idea, she asked a number of patients undergoing amputation to take a drug called memantine. 为了检验这个想法，她让进行截肢的病人服用一种叫美金刚胺(Memantine)的药物。
- This paper introduces mechanism of action,pharmacokinetics and determination of Memantine. 现综述其作用机制、体内过程与测定技术。
- Thirteen patients took memantine for four weeks after their amputations (and sometimes just before, as well). 13名病人在他们截肢之后（有些病人也在截肢前）服用美金刚胺持续4个星期。
- Memantine,a low-to moderate-affinity,uncompetive NMDA receptor antagonist,was approved for treatment of moderate to severe Alzheimer's disease. 美金刚是一种低中度亲和力、非竞争性NMDA受体拮抗剂,已被批准用于治疗中、重度阿尔茨海默氏病。
- Memantine hydrochloride was synthesized from 1,3 dimethyladamantane by bromination, acetamidation with acetonitrile in sulfuric acid and hydrolysis with an overall yield of 67.8%. 以1;3-二甲基金刚烷为原料;经溴化、乙腈和硫酸的作用下乙酰胺基化、水解、成盐等反应及改进的后处理方法得到盐酸美金刚;总收率67.;8%25。
- Memantine Hydrochloride is developed by German and comes into market, in China, which belongs to new drug of third classification at the phase of development. 盐酸美金刚由德国研制上市，国内处于新药研发阶段，属国家三类新药。
- To their delight, they discovered that memantine not only reduced changes in the brain, it also decreased both the incidence and the intensity of phantom pain. 让他们欣慰的是，他们发现美金刚胺不但减少了大脑的改变，而且也降低了患肢疼痛的次数和强度。
- The synthesis, properties and application of N,N - Dimethyl Acrylamide( DMAA) are introduced. The DMAA is a fine chemical raw material and has a bright developing and using future. 介绍了N,N-二甲基丙烯酰胺(DMAA)的合成、性能及其应用情况,认为N,N-二甲基丙烯酰胺是一种具有广泛开发应用前景的精细化工原料。
- Memantine has been prescribed for more than 20 years for various brain disorders, including dementia, because it is believed to protect against high levels of a neurotransmitter called glutamate. 美金刚胺已经被开给各种脑疾病的病人超过20年了，这些病人包括痴呆症患者。因为人们相信美金刚胺可以保护人脑免受过量的谷氨酸盐（一种神经递质）的损害。
- The project is of anti-risk ability, after the construction, the new formulations of Memantine Hydrochloride can be developed according to the markets, so which is better economic and social benefit. 该项目抗风险能力很强，项目建成后，可满足后续开发盐酸美金刚新剂型的需要，具有较好的经济效益和社会效益。
- Keywords cationic polymer;DMAA;ammonium salt; 阳离子聚合物;二甲基烯丙基胺;铵盐;
- Keywords Omethoate;Memantine;Experimental therapy; 氧乐果;美金刚;实验治疗;
- Keywords Memantine;Hypoxic-ischemic brain damage;Rats;newborn; 美金胺;缺氧缺血性脑损伤;新生大鼠;
- Keywords memantine;HSP70 gene;hypoxic ischemia;neonatal rat; 关键词美金胺;热休克蛋白70基因;缺氧缺血;新生大鼠;
- Keywords memantine hydrochloride alzheimer agent synthesis; 盐酸美金刚胺;痴呆症治疗药物;合成;
- Keywords memantine neonatal rats repeat dose toxicity; 美金胺新生大鼠重复用药毒性;
