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- High sense mutation of HVR 1 gene was found. （4）HVR1基因有义突变率相当高。
- Mutations in the ABCA 1 gene cause Tangier disease. ABCA 1基因的突变引起Tangier病 (TD)。
- Over expression of PAI 1 gene leads to mesangial ECM accumulation. 首次建立了系膜细胞PAI 1的过度表达体系 ,证实细胞过度表达PAI 1可以直接导致ECM的积聚。
- The carnosinase 1 gene produces an enzyme called carnosinase. 肌肽酶1基因翻译表达肌肽酶。
- GCH 1 gene mutation is only one of reasons to the DRD patients onset. GCH-1基因突变只是部分DRD患者的发病原因。
- Study on expression of IRF?1 gene in human leukemia with RT?PCR and the silver sequence techniques. 逆转录-聚合酶链反应银染分析IRF-1基因在白血病中的表达
- Results 1. The emm 1 gene and emm 3 gene were amplified and identified by blast to CDC data bank. 结果从40381137(T1)和31281187(T3)A组链球菌株的基因组成功克隆emm基因,经测序及blast后分别确认为emm1型和emm3型;
- Genetic heterogeneity existed among clinical isolates,and the major class of the flp 1 gene was class 2. Aa临床分离菌株flp 1基因具有遗传多样性 ,基因型主要为 2型
- Type III collagen is one main type of IMC, which is encoded by Col3a1(collagen type III alpha 1 gene). III型胶原是IMC的主要类型之一,其编码基因为Col3a1(Collagen type III alpha 1 gene)。
- Objective To investigate in Chinese population the relationship between GTP cyclohydrolase 1 gene mutation and phenotypes of dopa-responsive dystonia(DRD). 目的 分析国人多巴敏感性肌张力障碍（DRD）患者三磷酸鸟苷环羟化酶1（GCH-1）基因突变与表现型的关系。
- The organization of the Ers-MIH 1 gene is iden t ical to that of the molt-inhibiting hormone gene of Charybdis feriatus and Cancer pagurus. 中华绒螯蟹MIH 1基因的组织方式与斑纹?和食用黄道蟹的MIH基因相同。
- Compared with Gambia isolate, the FEN 1 gene of FCC1/HN isolate has 6 base pairs deletion at 1 581- 1 586 bp and other 5 bp mutations. 测序表明,恶性疟原虫FCC1/HN株与国外Gambia株和3D7株的FEN 1基因序列有较高的同源性。
- The expression of IL 1 gene was low in HCE16/3 cells normally. When HCE16/3 cells were co cultured with fibroblasts, however, the expression of IL 1 gene was significantly up? 在正常情况下 ,HCE16 /3细胞IL 1基因表达水平很低 ,但在与纤维母细胞作共同培养时 ,IL 1基因的表达水平明显上调。
- The successful cloning and expressing of vp 1 gene become thebasis for the immunological studies of VP1 protein and themanufacture of genetic engineering vaccine of CAV. vp1基因的成功克隆与表达，为VP1蛋白的免疫学研究和CAV基因工程疫苗的研制奠定了基础。
- The frequency of Gly972Arg mutation of IRS 1 gene was 2% in type 2 diabetic patients and control subjects in Chinese, lower than in Caucasian population. IRS- 1基因 Gly972 Arg突变频率在病例组和对照组均为 2%25 ,明显低于白人。
- AML 1 gene abnormalities, including both chromosome translocation and mutation (point mutation, insertion, deletion mutation, et al), which lead to the lost of transcript activation, are general in acute leukemia. 在急性白血病中常见AML1基因结构异常，包括平衡易位及突变(如点突变、插入或缺失突变等)，导致AML1的转录活性丧失，提示此基因功能缺失在急性白血病的发生及发展中起着重要作用。
- METHODS: Eukaryotic expression vectors pTL 8/apical membrane antigen 1 (AMA 1) (tTA) and pTL 8/AMA 1(rtTA)gene which express trans activator (tTA) or reverse trans activator(rtTA), respectively, and AMA 1 gene of Plasmodium falciparum were constructed. 方法 :首先构建恶性疟原虫顶端膜抗原 1(AMA 1)基因和转录激活因子 (tTA或rtTA)基因的真核表达质粒pTL 8/AMA 1和pTL 8/AMA 1(rtTA) ,并大量制备这两种质粒及表达转录抑制子 (tTS)的质粒pUHS6 1。
- Methods Four members of a DRD family were performed phenylalanine(Phe) and BH 4 loading test as well as urinary pterin analysis. Mutation analysis of GTP cyclohydrolase 1 gene(GCH1) was done in all family members. 方法 对DRD的一家系 4人进行苯丙氨酸 (Phe)和BH4负荷试验、尿蝶呤谱分析 ,对所有成员进行三磷酸鸟苷环化水解酶 1基因 (GCH1)检测。
- DJ, Party Promotor, Light Designer &operator. 派对策划;资深灯光设计师.
- Methods HLA?DQA?1 and DQB?1 gene polymorphism was tested in 30 CLT patients and 24 normal controls of Chinese Han nationality by using DNA amplification with polymerase chain reaction of sequence?specific primers (PCR?SSP). 方法用序列特异性引物的聚合酶链反应（PCR?SSP）方法，分析30例由病理证实的我国汉族CLT患者及24名正常对照的外周血白细胞基因组DNA的HLA?DQA1及DQB1位点的基因多态性分布。
