DDB at the concentration of 10-4M could significantly increase the content of cAMP in Bel-7402 cells,and also suppressed the expressions of oncogene c-myc and hepatocarcinoma marker AFP gene and enhanced the anti-oncogene p53 expression.
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- DDB还能明显增加Bel/7402细胞环化腺苷酸(cAMP)的含量,并抑制癌基因c-myc及肝癌标志AFP基因的表达,增强了P53抑癌基因的表达。