DCC and UNC5H1 are coreceptors for Netrin-4. However, because the binding affinity of Netrin-4 with its receptor was lower than that of Netrin-1, it could be inferred that there should exist unique receptor(s) for Netrin-4 other than DCC and UNC5H1.

 
  • DCC和UNC5H1可能是Netrin-1与Netrin-4的共受体。 由于Netrin-4受体结合动力学及受体竞争结合实验显示Netrin-1与受体的亲和力高于Netrin-4,提示Netrin-4可能还存在自身独特的受体。
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