Cytochrome P450 in insects is a supergene family.Increased detoxification of insecticides mediated by cytochrome P450s was proved to be an important and common mechanism of insecticide resistance.

• 细胞色素P450是超基因家族,由其介导的杀虫剂代谢解毒的增强是昆虫产生抗药性的普遍而主要的机制。