Conclusions The precursor lesions(tubular complexes) are formed by the transdifferentiation of acinar cells and some islet cells,with the incorporation of duct cells pre-existing in the lobules.

• 结论胰腺癌前体病变(导管复合体)除了由已经存在于小叶内的导管细胞组成外,主要通过腺泡细胞转分化形成,同时,胰岛细胞在某种程度上也参与了导管复合体的形成。