Conclusions Equisetum n-butanol extract and its remainder can regulate the expression of Bcl-2 and Caspase-3 in SMCs of aorta wall of early AS to increase the apoptosis of SMCs to prevent the occurrence of early AS.

• Caspase-3高于模型组(P<0.；01)。 结论木贼正丁醇提取物及提取剩余物通过控制AS早期主动脉壁平滑肌细胞Bcl-2、Caspase-3表达；促进平滑肌细胞凋亡；阻止AS的进程。