Conclusions CSE decreases the membranous expression of ECD in AECs, but increases the cytoplamic expression.The change of ECD expression may mediate the airway epithelial injuries by smoking.

• 结论 CSE使AEC中ECD膜上表达下调，胞浆内表达增高，该表达变化可能介导了吸烟对AEC的损伤作用。