Conclusion: IL-6 plays a role in the pathogenesis of posunenopsusal osteoporosis.Nilestriol can in hibit the expression of IL-6, reduce bone resorption, and maintain bone volume.

• 结论：IL-6参与调节雌激素撤退所致的骨吸收，尼尔雌醇可以抑制IL-6的基因表达，减少骨丢失，维持骨 量。