Conclusion Ulinastatin can reduce the increase of the cell adhesion molecules and proinflammatory cytokines during cardiopulmonary bypass and effectively weaken the inflammatory response to CPB.

• 结论：体外循环可引起细胞因子及黏附分子的表达上调，乌司他丁能抑制细胞因子的释放及黏附分子的表达，有利于减轻CPB所致的炎症反应。