Conclusion The low level of sex hormone changed in COPD male patients may contribute to the deep of the severity and occurrence of acute exacerbation.

• 结论 COPD的发作与性激素水平低下关系密切，性激素水平是COPD病理改变的结果，其低下的水平加重了COPD的病情，可能是COPD的独立危险因素。