Conclusion NCTD may decrease the proteinuria of protein-overload nephropathy rats and attenuate tubulointerstitial lesion without severe side effects of liver, kidney or bone marrow.

• 结论 去甲斑蝥素能显著降低蛋白负荷肾病大鼠尿蛋白，减轻其肾小管间质病理损伤，且无肝肾毒性及骨髓抑制等严重不良反应。