Conclusion Inhibition of EGFR signaling can delay endochondral ossification, osteoclast recruitment and decrease osteoclast formation.

• 结论：EGFR信号转导机制可能通过调节破骨细胞的生成，影响其向中心生长板的募集，从而影响小鼠初级软骨内骨化的进展。