Conclusion High-dose IVIG can effectively arrest the progression of hemolytic disease, quickly reduce serum total billirubin concentration and shorten phototherapy time for early treatment of ABO-HDN.

• 结论早期大剂量IVIG能有效阻断溶血的继续发生,快速降低血清总胆红素,降低核黄疸的发生率,大大缩短光疗时间,是早期治疗新生儿ABO-HDN的有效手段。