Conclusion Cellular immunity in mice could be enhanced induced by DNA vaccines based on HPV16 E6/E7. It could be much stronger induced by DNA recombinants of HSP70 of mycobacterium tuberculosis and HPV16 E6/E7. However, humoral immunity remained.

• 与结核杆菌HSP70重组后,IL-10及抗体水平没有明显变化。 结论以HPV16 E6/E7为基础的DNA免疫能增强小鼠的细胞免疫反应。