Compared with control mice receiving no AFG 1, bronchial epithelial hyperplasia, alveolar hyperplasia and adenocarcinoma of lung were observed in mice receiving AFG 1 treatment.

• 对照组动物各器官组织均未见明显病理改变。 AFG1各处理组均有部分动物发生支气管上皮增生、肺泡上皮增生和肺腺癌。