Compared with acid and alkaline condition, rhBMP-2m refolded in neutral condition has the best activity of inducing the formation of bone, but rhBMP-2m refolded in acid condition has better dissolubility.

• 相比酸性和碱性条件；中性条件下复性的rh-BMP-2m的诱骨活性最好；但酸性条件下复性的rhBMP-2m溶解度好.