Combined DNA vaccine encoding Ag85B, MPT64 and MPT83 of Mycobacterium tuberculosis were formulated into DDA and MPL to immunize mice and then the immunogenicity and protective efficacy of each group were evaluated.
英
美
- 编码结核杆菌3种抗原Ag85B；MPT64；MPT83的基因片段插入真核表达载体作为组合疫苗免疫小鼠；DDA和MPL作为佐剂分别提高了此三价苗的免疫原性和免疫保护效果；且相比之下DDA优于MPL.
