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- Objective: To evaluate the experession of Collagen type IV in hydronephrotic kidneys and its clinical implications. 摘要目的:研究IV型胶原在肾积水中的表达及意义,并探讨其沈积与小管间质纤维化程度的相关性。
- Methods: Collagen type IV expression was detected in 31 cases of hydronephrosis tissues and 13 cases of normal kidney tissues by S-P immunohistochemical method. 方法:采用免疫组织化学方法(S-P法),检测IV型胶原在31例肾积水和13例正常肾组织中的表达情况。
- Conclusion: The deposition of Collagen type IV might contribute to alterations in tubular function and play a great role in the development of tubulo-interstitial fibrosis. 结论:IV型胶原沈积可能造成小管功能改变,是梗阻肾小管门质纤维化进程中的一个重要因素。
- This study was performed to investigate whether overexpression of ECM components, laminin (LM) and collagen type IV (Col) by TM cells may play a role in the development of outflow resistance. 实验目的:研究小梁细胞合成的细胞外基质成分层粘连蛋白和IV型胶原是否影响房水流出阻力的形成。
- Results At the late stage of glaucoma, the labeling of collagen type IV and laminin were increased at pre LC and LC area due to the accumulation of basement membrane like materials. 结果与正常猴视乳头相比,早、中期青光眼模型视乳头筛板无明显变化。
- Collagen type IV alpha 2 (COL4A2) Ⅳ型胶原α2链(COL4A2)
- Collagen type IV 胶原Ⅳ型
- Immunostaining of type IV collagen and laminin in VH and VC displayed intact basement membrane, but presented non-continuous banding type in SCC. 第四型胶原蛋白及板层素免疫组织化学染色,在疣状上皮增生及疣状癌呈现完整基底膜染色,但在鳞状细胞癌则呈现非连续的带状染色型态。
- Serum hyalaronic acid (HA), laminin(LM) and type IV collagen (IV-C) content determined before and after treatment. 治疗前后测定血清肝纤维化指标透明质酸酶(HA),层粘连蛋白(LN),IV型胶原(IV-C)。
- Objective: To determine the expression of laminin (LN) and type IV collagen in patients with leukoplakia and squamous cell carcinoma of vulvae. 目的:研究层黏连蛋白(LN)和IV型胶原在外阴白斑和外阴鳞癌中的表达。
- Objective:To study the relationship between serum hyalurionic acid(HA),laminin(LN),type IV collagen(IV-C) and hepatic fibr osis or primary liver cancer(PLC). 目的:研究血清透明质酸(HA)、层粘连蛋白(LN)及IV型胶原(IV-C)水平与肝纤维化及肝癌转移的关系。
- Abstract: Objective:To study the relationship between serum hyalurionic acid(HA),laminin(LN),type IV collagen(IV-C) and hepatic fibr osis or primary liver cancer(PLC). 摘 要: 目的:研究血清透明质酸(HA)、层粘连蛋白(LN)及IV型胶原(IV-C)水平与肝纤维化及肝癌转移的关系。
- Objective:To study the relationship between serum hyalurionic acid(HA),laminin(LN),type IV collagen(IV-C) and hepatic fibrosis or primary liver cancer(PLC). 目的 :研究血清透明质酸 (HA)、层粘连蛋白 (LN)及IV型胶原 (IV -C)水平与肝纤维化及肝癌转移的关系。
- The new Type IV alloys and racing rims form the top version. 新的合金和IV型赛车轮圈形成顶部的版本。
- After incubation with Cpd 861 for 48 hours, HSC was harvested to determine collagen type I,III,IV mRNA by dot blot hybridization and cell culture medium was used to detect collagen secretion by ELISA method. 传一代细胞以10mg/ml复方861作用48小时后 ,以ELISA法、斑点杂交法检测胶原蛋白分泌及相应mRNA水平的变化。
- In light of the above results, we suggest that a combination of AgNORs and immunohistochemical staining of PCNA, type IV collagen, and laminin might be used as a method for distinguishing the differences among oral VH, VC and SCC. 由以上的结果,我们认为合并使用核仁组成区嗜银蛋白染色及增殖细胞核抗原、四型胶原蛋白及板层素之免疫组织化学染色,可做为口腔之疣状上皮增生、状癌与鳞状细胞癌鉴别诊断上的参考。
- The aim of this study was to evaluate the differences among oral VH, VC and SCC by silver-binding nuclear organizer regions stain( AgNORs) and immunohistochemical staining for proliferating cell nuclear antigen( PCNA), type IV collagen and laminin. 本研究目的希望藉由核仁组成区嗜银蛋白染色,以及增殖细胞核抗原、四型胶原蛋白及板层素之免疫组织化学染色,做为疣状上皮增生、状癌与鳞状细胞癌之区别。
- Objective To investigate whether aldosterone (Aldo) may be synthesized by glomerular mesangial cells and whether Aldo promotes the synthesis of fibronectin (FN) and type IV collagen in mesangial cells. 目的 证明肾脏系膜细胞能够自身合成醛固酮 ,并探讨醛固酮对系膜细胞细胞外基质生成的影响。 方法 用RT PCR法检测大鼠系膜细胞醛固酮合成酶CYP11B2mRNA表达 ,PCR产物存化后直接测序 ;
- Among these MMPs, the type IV collagenases ( MMP-2 and MMP-9) are particularly important in tissue infiltration by PMNs during inflammation because of the abundance of type IV collagen in the vascular basement membrane. 在MMPs家族中,W型胶原蛋白酶(MMP一和MMP习)在炎症过程的PMNS组织浸润中尤其重要,因为W型胶原蛋白在血管基底膜中是十分丰富的。
- Collagen (type IV in basement membrane and types V and VI as fine fibrils) comprises the structural component of ECM that provides shape and stability. 胶原是细胞外基质的结构性成份,维持形状和稳定性。
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