Cirrhotic Kupffer cells also had increased densities of functional receptors for both PAF and ET-1(exclusively ETB),but did not change the affinity of these receptors. No mRNA transcripts for the ETA receptor or preproET-1 were detected.

• 肝硬化组Kupffer细胞PAF及ETB受体mRNA水平及受体密度明显增加,而受体亲和力无变化,无ETA受体和ppET-1 mRNA表达。