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- Chronic morphine tolerance 慢性吗啡耐受
- Putrescine could attenuate the development of morphine tolerance, and treat morphine tolerance which was developed. 腐胺能够减弱吗啡耐受的形成,对已形成的吗啡耐受也有治疗作用;
- It suggests that putrescine has potential of treating morphine tolerance and dependence. 结论 腐胺和胍丁胺具有相似的生物学活性,具有治疗阿片耐受和依赖的潜力。
- Am binding inhibitor in someselected brain regions of chronic morphine dependent rats at different time-points. 地西泮结合抑制因子基因在慢性吗啡依赖大鼠部分脑区。
- Glutamate transporters play an important role in morphine analgesics,morphine tolerance and neuropathic pain. 谷氨酸转运体在吗啡镇痛及耐受中扮演一定的角色,并在神经病理性痛中发挥重要作用。
- Conclusion Putrescine has similar biological activities to agmatine.It suggests that putrescine has potential of treating morphine tolerance and dependence. 结论 腐胺和胍丁胺具有相似的生物学活性,具有治疗阿片耐受和依赖的潜力。
- Nitric oxide, an intracellular messenger molecule linked to activation of N Methyl D aspartate(NMDA) receptor, plays a role in morphine tolerance and dependence. 一氧化氮(NO)是与N甲基D天(门)冬氨酸(NMDA)受体活性相关的一种细胞内信使分子,在吗啡耐受和依赖中起作用。
- Gi_2 proteins in chronic morphine dependent group and chronic abstinence group were significantly decreased in nucleus accumbens (P<0.01) and significantly increased in locus coeruleus (P<0.05) compared with that of chronic control group. 慢性吗啡依赖组和戒断组与慢性空白对照组比较;NAc区Gi2蛋白水平明显降低(P<0·01);LC区Gi2蛋白水平明显升高(P<0·01)。
- Conclusion: Chronic morphine treatment can increase IA current density of newborn rat cortical neurons,making the neurons in its hyperpolarization state,and inhibit the activity of the neurons. 结论:吗啡能引起神经细胞IA增强,使神经元处于超极化状态,导致其活动抑制。
- RPS was found to suppress this decrease and increase the antinociception effect of morphine in acute morphine tolerant rats. 重楼皂甙对这一回降过程有抑制作用 ,并增强吗啡对急性吗啡耐受大鼠痛阈的提高作用。
- rylation by acute and chronic morphine in rat locus coeruleus[ J] . 作者简介:李国海(1965-),男,江苏镇江人,副主任医师,医学博士
- Related neural mechanisms between visceral hyperalgesia and morphine tolerance 吗啡耐受及内脏痛敏的相关机理
- Postmortem redistribution of morphine in rats with chronic morphine poisoning 吗啡在慢性染毒大鼠体内死后再分布
- There is a chronic unemployment problem in America. 在美国存在长期失业问题。
- My brother has chronic bronchitis. 我的哥哥患有慢性支气管炎。
- The morphine was administered by injection. 那吗啡是注射进去的。
- This has gone beyond the gauge of her tolerance. 这已超出她的忍受范围。
- Assuage their chronic insecurity. 消除他们长期的不安全感
- Effects of morphine tolerance on astrocytes of spinal cord posterior horn in rats 吗啡耐受对大鼠脊髓后角星形胶质细胞的影响
- The principal reprimand the student for his chronic lateness. 校长斥责那个学生不该接二连三地迟到。