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- Objective To investigate the relationship among apoA1,immunoglobulin IgA,IgM,IgG and cholesterol gallstone formation. 目的探讨抑成核因子载脂蛋白A1 (apoA1 )、促成核因子免疫球蛋白IgA、IgM、IgG与胆囊胆固醇结石形成的关系。
- Piperine may prevent the formation of cholesterol gallstone through inhibiting the lithogenic role of APN. 以上结果表明胡椒碱主要通过降低肝APN的表达及胆汁APN酶的活性 ,抑制APN的促成石作用而预防胆固醇结石的形成。
- Cholesterol supersaturation and precipitation from bile is the main reason for cholesterol gallstone formation. 胆固醇结石形成最主要的原因是胆汁中胆固醇过饱和而从胆汁中析出。
- Objective To explore the relationship between the mRNA expression of ABCG5 and ABCG8 in gallbladder mucosa and cholesterol gallstone disease (GS). 目的探讨ABCG5和ABCG8基因在胆囊黏膜中的表达与胆固醇结石病的关系。
- The golden syrian hamster is an excellent experimental animal for cholelithiasis model for both cholesterol gallstone and pigment gallstone. 叙利亚金黄地鼠是研究两类胆石形成的良好实验动物之一。
- To determine the changes of gastrointestinal migrating motor complex(MMC)during the early stage of cholesterol gallstone formation. 探讨胆固醇结石形成早期胃肠移行性复合运动(MMC)变化。
- Objective To observe the inhibiting effect on cholesterol gallstone formation by drug-induced hepatic bilirubin UDP-glucuronosyltrasferase (B-UGT) gene expression. 目的通过药物诱导肝脏胆红素尿苷二磷酸葡萄糖醛酸转移酶(B-UGT)基因表达，观察其对胆固醇结石形成的抑制作用。
- Objective To survey carboxypeptidase E(CPE) mRNA expression by cDNA microarray and real-time PCR in the liver of patients with cholesterol gallstone(CGS),and to reveal the role of CPE in the formation of CGS. 目的:利用基因芯片和实时定量聚合酶链反应(real-time PCR)分析胆囊胆固醇结石病人肝脏中羧肽酶E(carboxypeptidase E,CPE)的mRNA表达,探讨CPE与胆囊胆固醇结石形成可能相关的分子机制。
- Objective To investigate the expression and distribution of scavenger receptor class B type I(SR-BI) in the mucosa of patients with cholesterol gallstone,and analyze their relationship. 目的探讨SR-BI在胆囊胆固醇结石病人胆囊粘膜中的表达和分布,了解其与胆固醇结石发病之间的关系。
- The change in APN activity was observed after UDCA therapy in patients with cholesterol gallstones. 测定胆囊胆汁中蛋白质、APN活性、胆固醇、磷脂、胆盐、胆固醇饱和指数，比较各组结果。
- Conclusions There is difference in APN activity in gallbladder bile between patients with cholesterol gallstones and those without them. 结论本实验显示胆固醇结石病人与无结石者之间存在着APN活性上的差别；
- Keywords azintamide;guinea pig;cholesterol gallstone;mucin; 阿嗪米特;豚鼠;胆固醇结石;黏液素;
- UDCA therapy not only decreases CSI(cholesterol saturation index) but also lowers APN activity in gallbladder bile of patients with cholesterol gallstones. UDCA能够在降低胆固醇饱和指数的同时，也降低APN活性。
- These suggest that the decreased activity of LDL receptor of hepatocytes would reduce the synthesis of GCA, thus resulting in the formation of cholesterol gallstones. 上述结果提示： 肝细胞低密度脂蛋白受体活性下降，可能导致胆汁中甘氨胆酸减少，致成石性胆汁形成。
- Cholesterol in the bile can form painful gallstone. 胆汁里的胆固醇能形成让人感到疼痛的胆结石。
- Keywords SCP 2;gene expression;lithogenic biles;cholesterol gallstone;heredity; 蛋白表达;致石性胆汁;胆固醇结石;家族遗传性;
- Keywords carboxypeptidase E;Cholesterol gallstone;Gene expression;Liver; 羧肽酶类;胆结石;基因表达;肝;
- Keywords Cholesterol gallstone;Serum lipid;Lipoprotein;Apolipoprotein; 胆固醇结石;血脂;脂蛋白;载脂蛋白;
- Detection of Single Nucleotide Polymorphism in Sterol Garrier Protein 2 Gene of Cholesterol Gallstone Patients 胆固醇结石患者固醇携带蛋白2基因单核苷酸多态性的检测
- Experimental study of bear bile in prevention of cholesterol gallstone of guinea pigs 熊胆预防豚鼠胆囊胆固醇结石的实验研究
