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- The divergence of chemokine or chemokine receptors was earlier than the divergence of vertebrates. 可见基因家族成员的分化早于脊椎动物的分化。
- Chemokine receptors such as CCR5 and CXCR4 are found as coreceptor to enter the host cell by HIV. 摘要趋化因子受体是HIV进入宿主细胞的共受体,特别是CCR5和CXCR4在HIV进入免疫细胞过程中起着重要作用。
- Chemokine receptors such as CCR5 and CXCR4 are fou nd as coreceptor to enter the host cell by HIV. 趋化因子受体是HIV进入宿主细胞的共受体,特别是CCR5和CXCR4在HIV进入免疫细胞过程中起着重要作用。
- The divergence of chemokine receptors was earlier than the dovergence of vertebrates. 可见基因家族成员的分化早于脊椎动物的分化。
- At present, chemokine receptors have become the new target of the drug research. 目前,趋化因子受体已经成为药物研究的新靶点。
- Chemotaxis assays were used to verify functionality of these chemokine receptors. 使用趋化作用分析来证实这些趋化因子受体的功能性。
- Chemokine receptors and their ligands play an important role in tissue-specific homing of leukocytes. 趋化因子受体和它们的配体在粒细胞组织特异性定位中起重要作用。
- Chemokine receptors are the members of the G-protein coupled receptor(GPCR) supergene family which include seven hepatahelical transmembrane peptides. 趋化因子受体属于G蛋白偶联受体超家族,是含7个穿膜区段的单链受体,胞内区与G蛋白偶联,可产生信号转导。
- The chemokine receptors, CXCR4 and CXCR6 were universally transcribed in each endometrial tissue and endometriotic foci. RT-PCR结果显示CXCR4、CXCR6在正常生育期子宫内膜、EMT患者在位子宫内膜及异位灶组织均普遍中度表达。
- The chemokine receptor CXCR6 and its ligand CXCL16 are involved in inflammation. 趋化因子受体CXCR6 及其配体CXCL16的作用是参与炎症。
- Chemokine receptors are the members of the G-protein coupled receptor(GPCR)(supergene) family which include seven hepatahelical transmembrane peptides. 趋化因子受体属于G蛋白偶联受体超家族,是含7个穿膜区段的单链受体,胞内区与G蛋白偶联,可产生信号转导。
- The molecular evolutionary rates of chemokine receptor genes are different, with CXCR4 gene scored the lowest. 趋化因子受体的进化速率不同,其中CXCR4的进化速率最低。
- Abstract: Objective To explore the correlation between structure domains and function of chemokine receptor CXCR4. 摘 要: 目的 认识趋化因子受体CXCR4之结构与功能的关系。
- The aim of this article is to review recent devel-opment of CCR7,a newly identified chemokine receptor,and its ligand CCL21and CCL19. 全文就新近发现的趋化因子受体CCR7及其配体CCL21和CCL19的研究进展作一综述。
- Objective To investigate whether homocysteine (HCY) can induce the expression of chemokine receptor CCR1 mRNA in cultured THP-1 monocytes. 目的 探讨同型半胱氨酸对人单核细胞株THP 1表达趋化因子受体CCR1mRNA的影响。
- Objective To investigate the role of CC chemokine receptor 5(CCR5) in the immunological pathogenesis of hepatitis B(HB). 目的研究细胞趋化因子受体5(CCR5)在乙型病毒性肝炎(HB)免疫发病机制中的作用。
- AIM:To investigate the expression of CC chemokine receptor 7 (CCR7) in different types of lung carcinoma and its clinical significance. 目的:探讨趋化因子受体CCR7在不同类型肺癌组织中的表达及其临床意义。
- Chemokine CCL21 is a ligand of chemokine receptor (CCR)7. It is constitutively expressed at high level in secondary lymphoid organs (thymus, lymph node, spleen). 趋化因子CCL21是趋化因子受体(CCR)7的一个配体。 它在次级淋巴器官(胸腺、淋巴结、脾脏)中组成性高表达。
- Objective To explore the relationship between chemokine receptor CCR5, CCR2 gene polymorphism and Chinese type 1 diabetics, as well as their first relatives. 目的 探讨趋化因子受体CCR2、CCR5基因多态性与 1型糖尿病 (T1DM)及其一级亲属之间的关系 ,并与T2DM及非DM对照进行比较。
- Thymus and activation -regulated chemokine (TARC) , a CC chemokine, was identified as a selective chemoattractant for CC chemokine receptor 4 (CCR4) - expressing cells to ti-uss. 胸腺和活化调节趋化因子(thymus and activation-regulated chemokine,TARC)是CC型趋化因子,其受体是CC趋化因子受体4(CC chemokine receptor 4,CCR4),在活化的Th2细胞上呈优势表达,它们共同作用使Th2细胞由血液迁移到一定的组织中。