Chemically synthesized short survivin-siRNA can effectively inhibit survivin expression and cell proliferation in osteosarcoma cell line MG-63.Short survivin-siRNA may be a useful therapeutic strategy for cancer through the regulation of gene expression.

• 化学合成的survivin-siRNA能有效抑制survivin基因在骨肉瘤MG-63细胞中的表达,并对骨肉瘤MG-63细胞增殖有抑制作用。