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- Objective:To analyze the efficiency of delivery for CD8+ T cell epitope by attenuated E. 目的:分析体外、体内重组减毒大肠杆菌运送真核表达的CD8+T细胞表位的效应。
- Conclusions The method of synthetic pe ptides plus anti-CD28 antibody was feasible for locating T cell epitope s on superantigens. 结论超抗原合成肽结合CD28抗体的方法对寻找超抗原T细胞识别表位是切实可行的。
- Furthermore, immunization with NPs carrying a CD8(+) T cell epitope peptide of Listeria monocytogenes significantly protected the infected mice from death. 此外,携带Listeria单核细胞CD8(+)T细胞表位多肽的纳米颗粒能有效的保护被感染的小鼠免于死亡。
- The oncoprotein encoded by E7 gene is considered as ideal specific antigen against HPV associated cancer. The E7 oncoprotein is characterized by several linear B cell epitope, CD4+T cell epitope and CD8+ cell epitope. 由HPVl6E7基因产生的早期蛋白E7与细胞的转化和恶性变密切相关,并且被认为是HPV相关肿瘤特异性肿瘤排斥抗原,含有多个线性B细胞表位、CD4+T细胞表位和CD8+CTL表位。
- Both of the common methods of experimental determination and theorical prediction for identifying T cell antigen epitope and the methods of T cell epitope analysis were summarized. 综述了近年来实验确定和理论预测T细胞蛋白质抗原表位的常用方法,以及T细胞抗原表位分析的研究方法。
- Partial mapping the associated B cell epitope in pp65 antigen found that only the pp65-3, that cover one third of the entire pp65 on the C terminal, was recognized by sera of SLE patients. 进一步分析,发现只有在靠近pp65 蛋白质C 端,约全长三分之一大小的片段(我们命名为pp65-3 )会被红斑性狼疮病人血清辨识。
- The C terminus of NP contains the type-specific B cell epitopes, which occupies C terminus, about half of NP. 上述研究结果提示,体外表达NP蛋白的高变区,有可能用于汉坦病毒的分型检测研究。
- Objective To establish an effective method for loc ating T cell epitopes on superantigens. 目的建立一种有效的探找超抗原T细胞识别表位的新方法。
- Keywords Avian influenza;Vaccine;T cell epitope;Samonella;Fimbriae; 禽流感;疫苗;T细胞抗原表位;沙门氏菌;菌毛;
- Keywords Clostridium botulinum;botulinum neurotoxin;B cell epitope; 肉毒梭菌;肉毒神经毒素;B细胞表位;
- Keywords Th cell epitop;DNA vaccine;splicing by overlap extension; 辅助细胞表位;DNA疫苗;互补延伸拼接;
- A storage cell in some amorphous memory devices. 某些非晶体存储器中的一个存储单元。
- She was found prostrate on the floor of the cell. 有人发现她趴在小屋的地板上。
- Keywords Trichinella spiralis;ES antigen;secondary structure;B cell epitope; 关键词旋毛虫;ES抗原;二级结构;B细胞表位;
- Methods Based on SARS coronavirus genome sequence and the analysis of the flexible regions of secondary structure for S protein, the B cell epitopes for S protein were predicted by methods of Kyte Doolittle hydrophilicity plot, Emini, and Jameson Wolf. 方法 基于SARS蛋白基因组序列 ,采用Kyte Doolittle的亲水性方案 ,Emini方案和Jameson Wolf抗原指数方案 ,辅以对S蛋白的二级结构中的柔性区域的分析 ,预测SARS病毒S蛋白的B细胞表位。
- Bioinformatics were applied for analyzing recombination patterns and gene mutations of the IgHV genes. Softwares SYFPEITHI and BIMAS were used for predicting the T cell epitopes in the immunoglobulin heavy chain variable regions. 利用互联网生物信息资源分析B ALLIgHV基因的重排类型和基因变异 ,利用SYFPEITHI和BIMAS软件预测IgHV基因编码蛋白质的T细胞表位。
- The prisoner rapped out a message on the cell wall. 那囚犯敲打囚室的墙来传达讯息。
- This review summarizes theory and method-ology of prediction for helper T cell epitopes, and their application in vaccine development against parasites, and new research directions are also discussed. 本文概述辅助T细胞表位预测的理论和方法及其在寄生虫疫苗研发中的应用,并讨论未来的研究方向。
- The prisoner raped out a message on the cell wall. 那囚犯敲打囚室的墙来传达讯息。
- The growth of successive layers of a cell wall. 敷着,附着细胞壁连续层的生长