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- Keywords Schistosoma japonicum;cathepsin B endopeptidase;nucleic acid vaccine;immunization; 日本血吸虫;组织蛋白酶B;核酸疫苗;免疫;
- Cathepsin B Endopeptidase 组织蛋白酶B
- Conclusion the expression of cathepsin B in human gastric adenocarcinoma shows an obvious increasing tendency. 结论人胃癌组织中组织蛋白酶B的表达明显升高。
- Sloane BF,Dunn JR,Honn KV.Lysosomal cathepsin B:Correlation with metastatic potential[J].Science,1981,212:1151. 蒯小玲,萧树东,刘文忠,等.;重组组织蛋白酶B的表达与纯化[J]
- Cathepsin B(CB) is a well-known lysosomal cysteine protease which has been studied in association with cancer invasion and metastasis. 组织蛋白酶B(CB)是存在于人体正常组织的一种半胱氨酸蛋白酶,与肿瘤的侵袭和转移密切相关。
- Methods Cathepsin B expression in 54 specimens of human gastric adenocarcinoma was detected and studied by immunohistochemistry. 方法应用免疫组织化学方法研究54例胃腺癌标本中组织蛋白酶B的表达。
- Methods Immunohistochemical staining for cathepsin B was done by the streptavidin-biotin method in 20 renal cell carcinoma patients. 方法应用免疫组化技术测定组织蛋白酶B在肾癌患者癌组织和癌周组织中阳性的表达。
- Conclusion As an adjuvant, IL-4 DNA can improve the protective effect of cathepsin B DNA vaccine in mice against S. japonicum infection. 结论 重组IL-4 能提高日本血吸虫组织蛋白酶B 核酸疫苗的抗血吸虫保护力作用,具有佐剂的免疫效应。
- Objective To examine the inhibitory effects of human/murine chimeric anti- cathepsin B (Cat B) antibody on Cat B enzymatic activity against protein substrate in vitro. 目的 体外试验人 鼠嵌合抗人组织蛋白酶B(抗CatB)抗体对CatB的抑制作用。
- Invasive meningiomas expressed higher immunohistochemical score(4-6) of cathepsin B than did non invasive meningiomas ( x2=11.80, P<0.01; x2=5.61, P<0.05 ) . 侵袭性组中组织蛋白脑膜瘤中组织蛋白酶的异常表达及其临床价值中文摘要酶B的高免疫组织化学积分(4~6)率显著高于月限袭性脑膜瘤组(x、11 .;80,P<0
- Pretreated with 3-MA and cathepsin B inhibitor attenuated QA-induced internucleosomal DNA fragmentation and significantly reduced the striatal neuronal loss (P<0.01). 3-MA和cathcpsin B inhibitor给药组与模型组相比DNA ladder凋亡条带明显减弱;损伤面积显著减小(P<0.;01)。
- There was no obvious correlation between the expression of cathepsin B and the prognostic indexes of gastric carcinoma such as tumor histologic types and TNM stages. 组织蛋白酶B的表达与胃癌预后指标(肿瘤组织学类型,TNM分期)无明显相关性。
- Objective To test the expression of Cathepsin B (CB) protease in gliomas and to investigate its correlation with the malignance and angiogenesis of gliomas. 摘要目的探讨组织蛋白酶B(CB)在人胶质瘤中的表达及其与胶质瘤恶性程度、血管生成的关系。
- Objective To study the expression of cathepsin B in gastric carcinoma and its relationship with the prognostic indexes (tumor histologic types,TNM stages) of gastric carcinoma. 目的研究胃癌组织中组织蛋白酶B的表达及探讨组织蛋白酶B表达与胃癌预后指标(肿瘤组织学类型,TNM分期)的关系。
- Methods Balb/c mice were inoculated with CVB3m(Nancy strain). The expression of lysosome cathepsin B in myocardium samples were determined by immunohistochemical staining and RT-PCR on the 3rd day, 7th day , 15th day, 30th day post-infection. 方法 采用免疫组织化学技术和RT-PCR技术检测Balb/c小鼠感染和未感染CVB3m(Nancy株)病毒后心肌组织中d3、d7、d15、d30溶酶体组织蛋白酶B表达。
- Objective: To study the expression of cathepsin B (CB) in the 5/6 nephrectomized rat remnant kidney;to investigate the effects of Yanshen Capsule on the remnant kidney and the related mechanism. 目的:观察大鼠5/6肾切除术后不同时相点肾组织蛋白酶B表达变化及其意义以及延肾胶囊延缓残肾进行性损伤作用及其机理。
- Keywords ophiobolin;cathepsin B;anti-tumor; 蛇孢菌素;组织蛋白酶B;抗肿瘤作用;
- Cathepsin B ;Protease Inhibitors ; 组织蛋白酶B ;
- In English, b, p, m and w are bilabials. 英语中的b、p、m、w为双唇音。
- Keywords Renal fibrosis Cathepsin B Remnant kidney Rat; 肾纤维化;组织蛋白酶B;残肾;大鼠;