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- Cannabinoid receptor agonist 大麻素受体激动剂
- Objective To explore the protective effects of WIN55212-2,an agonist of cannabinoid receptor,on ischemia-reperfusion injury in isolated rat hearts. 目的探讨大麻素受体激动剂WIN55212-2对体外大鼠心肌缺血再灌注损伤的保护作用。
- The M receptor agonist pilocarpine was similar to the effects of ACh. M受体激动剂毛果芸香碱能产生与ACh相似的效应。
- Objective To investigate the effect of doparnine receptor agonist piribedil on dopamine transporter. 目的研究常用抗帕金森药多巴胺受体激动剂吡贝地尔(舒达)脑多巴胺转运体的影响。
- As the mice age, the cannabinoid receptor binds less frequently to a specific protein, which seems to diminish the animals' taste for alcohol. 小鼠变老时,大麻素受体与某特定蛋白质的结合变差,似乎会让动物比较不嗜酒。
- Clinical treatment of PD includes dopamine replacement such as L-DOPA and D_2 dopamine receptor agonist. 目前临床仍以替代治疗为主,左旋多巴和D_2受体激动剂能改善PD症状,但不能阻制疾病发展,这使人们对PD治疗的认识由单纯替代疗法逐渐转向保护中脑DA能神经元。
- Rotigotine is a non-ergolinic dopamine receptor agonist available as a patch for once-daily use. 罗替戈汀是现有非二氢麦角碱多巴胺受体激动剂中可作为每日一次使用的辅助药物。
- Another aspect of the invention is concerned with new and improved pyrazole analogs having high affinities and/or selectivities for the CB1 cannabinoid receptor. 本发明另一方面涉及对CB1大麻受体具有高亲合力和/或选择性的新的改良的吡唑类似物。
- Rotigotine is a non-ergolinic dopamine receptor agonist aailable as a patch for once-daily use. 罗替戈汀是现有非二氢麦角碱多巴胺受体激动剂中可作为每日一次使用的辅助药物。
- The great majority of these effects of THC are mediated by cannabinoid receptor type 1 (CB1), which is abundantly expressed in the central nervous system. THC产生的绝大部分作用是由大麻素受体1(CB1)引起的,这种受体在中枢神经系统中得到广泛表达。
- The citrated whole blood is tested at the basal and TRAP (Thrombin Receptor Agonist Peptide) activated states. 柠檬酸化的健康的血被测试在基础并且捕捉(凝血酶感受器官收缩筋肽)被激活的状态。
- A brief discussion is also given about the pr ospects of nicotinic receptor agonist used as non-opiate analgesics. 从地棘蛙素全合成研究、类似物制备、药理学行为和构效关系等几方面介绍了国际上研究的热点,并对今后的研究动向进行了讨论。
- The effects of receptor agonist and antagonist on hypnotic activity of melatonin were studied in the paper. 观察不同受体激动剂或拮抗剂对褪黑素催眠作用的影响。
- Objective: To study the protecting effect of delayed preconditioning with A1 selective adenosine receptor agonist in donor heart preservation. 目的:探讨腺苷A1受体激动剂延迟预处理对大鼠心脏的保护效果。
- The competition curves of inverse BDZ receptor agonist DMCM was illustrated in a biphasic way by a computer model of two sites. 反相激动剂DMCM竞争结合曲线亦具有双位点结合特性。
- Endorphins, a known substances produced in brains is an opioid receptor agonist which the brain produce in the presence of pain stimulus. 如果你一连几天、一天几次进行实验:诱发某人身感疼痛,再用吗啡为他止疼,到最后一天,悄悄用盐水取代吗啡,你会发现,此时盐水也能止痛。
- As a high-selective 5-HT1D receptor agonist, sumatriptan is mainly used as an emergency medicine in the treatment of migraine and cluster headache. 舒马曲坦为具有高度选择性的5-HT1D受体激动剂,主要用作偏头痛和丛集性头痛发作的急救药。
- So in fibrotic livers you can find cannabinoid receptors that have both anti- and pro-fibrogenic effects. 因此在发生纤维化的肝脏大麻素受体既有抗纤维化作用也有促纤维化作用。
- Marijuana happens to resemble the endocannabinoids enough to activate cannabinoid receptors. 碰巧植物大麻所含的成份与内生性大麻素的构造相近,而足以活化大麻受体。
- It turns out that there actually cannabinoid receptors in the liver once you have fibrosis. 事实上当发生肝纤维化时肝脏存在大麻素受体。