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- Candesartan ciexetil 坎地沙坦酯
- These findings suggest that candesartan has dosage-dependent, anti-inflammatory effects that are mediated by suppression of NF-B activation and chemokine expression. 这些研究表明，坎地沙坦是剂量依赖性、抗炎作用是通过抑制NF-B的活性和趋化因子表达介导的。
- Conclusion The antihypertensive therapy based on candesartan has a significant effecacy to ameliorate the carotid artery remodeling. 结论高血压患者应用以坎地沙坦为基础的降压治疗可改善动脉重塑。
- Objective To observe what is the candesartan effects on the carotid intimamedia thickness (IMT) in hypertensive patients. 摘要目的观察坎地沙坦是否能够改善高血压患者的颈动脉重塑。
- Comparative impact of enalapril, candesartan or metoprolol alone or in combination on ventricular remodelling in patients with congestive heart failure. 依那普利、坎地沙坦、美托洛尔单用或合用对充血性心衰患者心室重构的影响之比较。
- The company has developed the series of API like Candesartan Cilexetil , Valsartan , Irbesartan , Gliquidone ,Indapamide, Tibolone ,Adefovir Dipivoxil ,Argatroban , etc. 已开发原料药包括坎地沙坦酯，缬沙坦，厄贝沙坦，格列喹酮，吲达帕胺，替勃龙，阿德福韦酯，阿加曲班等。
- These findings suggest that candesartan has dosage-dependent, anti-inflammatory effects that are mediated by suppression of NF-B actiation and chemokine expression. 这些研究表明，坎地沙坦是剂量依赖性、抗炎作用是通过抑制NF-B的活性和趋化因子表达介导的。
- A large number of clinical trials showed that candesartan could reduce the cardiovascular mortality for heart failure and hospitalization for worsening heart failure. 大量临床研究结果表明坎地沙坦可降低心力衰竭病人心血管死亡率和因心力衰竭加重的住院率。
- This review sums up the recent result about candesartan in lowering blood pressure,protecting target organ,treating congestive heart failure and coronary heart disease. 本文综述了坎地沙坦在降压、靶器官保护、防治心力衰竭以及冠心病中的近期研究成果。
- Conclusions: The addition of spironolactone to candesartan has significant beneficial effects on LV reverse remodeling in patients with mild-to-moderate chronic systolic HF. 结论：坎地沙坦联合螺内酯治疗对轻中度慢性收缩性心力衰竭患者的LV逆重构有明显益处。
- Objective: To investigate the effect of Tianma Gouteng Ying combined candesartan in reversing the carotid vascular remodeling of essential hypertension(EH) patients. 摘要目的：观察天麻钩藤饮合用坎地沙坦是否能加速逆转高血压病患者颈动脉内膜-中膜厚度的重塑。
- Methods Candesartan cilexitil was prepared from 3-nitro-1,2-benzenedicarboxylic acid via ten reactions,including esterification reaction,chlorination reaction,Curtis rearrangement,replacement reaction,etc. 方法设计了以 3 硝基 1,2 苯二甲酸为起始原料 ,经酯化、氯化、Curtis重排、取代、还原、两步环合、酯基碱水解、酯化、转晶共 10步反应 ,制备得到目标化合物的合成路线。
- In corresponding studies of candesartan therapy in subjects with both type 1 and type 2 diabetes who had retinopathy at baseline, the drug failed to mitigate retinopathy progression. 在相应的1型和2型糖尿病视网膜病变坎地沙坦治疗研究中，该药物却不能减轻视网膜病变的进展。
- Angiotensin receptor blockers， the class of drugs to which candesartan belongs， are thought to reduce the actions of the hormone angiotensin II and therefore impact on the renin-angiotensin system. 坎地沙坦，属于一种血管紧张素受体阻断剂，可以降低血管紧张素受体II的作用并影响肾素血管紧张素系统。
- Keywords Heart failure;Candesartan;Fosinopril; 心力衰竭;坎地沙坦;福辛普利;
- compound candesartan cilexetil tablets 复方坎地沙坦酯片
- Candesartan cilexetial/hydrochlorothiazide 高血压
- Dizhiya ( Candesartan Cilexetil) 迪之雅
- Advance in Research of Angiotensin Receptor Blockades--Candesartan 坎地沙坦--血管紧张素受体拮抗剂的研究进展
