Caffeic acid and ferulic acid were shown to increase the mouse survival time induced by ET 1 iv administration and decrease the vasoconstrictions of isolated aortic rings.

• 咖啡酸和阿魏酸(ip) 能剂量依赖性地显著延长ET?1 致小鼠急性死亡时间,在离体器官可观察到咖啡酸与阿魏酸能拮抗ET?1的缩血管效应;