CONCLUSIONS:Hirudin could prevent PVR from being formed or developing and had protective function on retina,whose mechanism related to the decrease of density of PDGF in vitreous body.

• 结论：水蛭素能抑制PVR的形成和发展，对视网膜有保护作用，其作用机制与减少玻璃体中血小板源性生长因子(PDGF)的浓度有关。