CONCLUSION: Portal hypertension is one of the characteristics of DMN-induced fibrosis in rats, and change of liver sinusoid wall may be the major histopathological feature of portal vein hypertension.

• 结论:门脉高压是DMN肝纤维化大鼠的显著特征之一,肝窦壁病理变化是该模型门脉高压形成的主要组织学基础。