CONCLUSION: Base pair substitution mutation and frame shift mutation were caused by folpet in Ames test.And DNA breakage in human PMNC might be induced by folpet.

• 结论： 灭菌丹可引起鼠伤寒沙门氏菌碱基置换和移码突变，并可能损伤人外周血淋巴细胞DNA的完整性。