By using the UV and Li Cl compound mutagenic agents screening process,the protoplast mutation of lovastatin producing strain was conducted,and two high- yielding strains,BTL 2 3 and BT2 5 respectively were isolated.

• 采用紫外线 -氯化锂复合诱变洛伐汀产生菌原生质体 ,经原生质体再生获得高产菌株 BTL 2 3、BTL5 6。