But the intimal hyperplasia(IH) has been one of the major cause of the graft late failure, especially for the middle and small artery.

• 研究表明，再狭窄的主要机制是血管损伤局部中膜平滑肌细胞过度增殖，向内膜迁移及细胞外基质形成引起的内膜增生。