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- Brain Iron Metabolism and Neurodegenerative Diseases 脑铁代谢和神经变性性疾病
- Keywords Iron metabolism;Brain iron;Neurodegeneration; 铁代谢;脑铁;神经退行性变;
- Keywords Brain iron metabolism;Hepcidin;divalent metal transporter 1;Ferroportin1;RT-PCR;Mouse; 脑铁代谢;铁调素;二价金属离子转运体1;膜铁转运蛋白1;逆转录聚合酶链反应;小鼠;
- Keywords Ceruloplasmin;Brain iron metabolism;Aceruloplasminemia;Cell iron release;Cell iron uptake; 铜蓝蛋白;脑铁代谢;无铜蓝蛋白血症;细胞铁摄取;细胞铁释放;
- Brain iron metabolism 脑铁代谢
- The excess iron accumulation in the brain may lead by the disrupted expression or function of iron metabolism proteins induced by either genetic or nongenetic factors. 研究显示 ,脑铁过量积聚主要是由于遗传性和非遗传性因素所引起的某些脑铁代谢蛋白功能异常或表达失控。
- Objective:To explore the regulatory mechanism of iron responsive element binding protein(IRE?BP) in iron metabolism. 目的:探索铁代谢平衡中铁效应元件结合蛋白(IRE-BP)的调节机制。
- It can improve iron metabolism at molecular level, raising Fe, TS, SF, lowering TIBC, Tf, sTfR. 在分子水平能改善铁代谢,提高Fe、TS、SF,降低TIBC、Tf、sTfR。
- Ferritins are ubiquitously distributed in organisms and take an important role in iron metabolism. 摘要铁蛋白是广泛存在于生物体内的储存铁的蛋白质,它参与生物体内的铁代谢。
- CONCLUSION Al overload may interfere with brain iron homeostasis, which may be responsible for neurodegeneration induced by Al toxicity. 结论 铝过负荷致神经元退变可能与其干扰脑铁代谢有关。
- Hemochromatosis is a disorder of iron metabolism of the body of a genetic disease. 血色病是因组织中铁的沉积过多而发生的全身性疾病。
- Neurodegeneration with brain iron accumulation (NBIA) is a rare, inherited, neurological movement disorder characterized by progressive degeneration of the nervous system. 什么是'神经退行性变与脑铁的积累-遗传疾病的异常运动'?
- Conclusion Glutamate and GABA in the substantia nigra may affect iron metabolism through DMT1-IRE and HP in the caudate putamen nucleus. 结论 黑质的谷氨酸和GABA可能通过影响尾壳核DMT1-IRE和HP的表达影响纹状体尾壳核的铁代谢。
- NO plays an important role in the disorder of iron metabolism in the ACD rat by establishing of the model of ACD rat successful-ly. 成功建立慢性病贫血大鼠模型,NO在ACD大鼠关节炎及铁代谢紊乱中起重要作用。
- Objective To explore the relationship between transferrin receptor (TfR) expression and cell proliferation capacity and iron metabolism status. 目的探讨急性白血病患儿外周血白血病细胞转铁蛋白受体表达与细胞增殖力和铁代谢的关系。
- The expression profile of 5 iron metabolism related genes of J774A.1 murine macrophages uninfected or infected with F. tularensis LVS was determined with real-time PCR. 用实时定量PCR法检测5个铁代谢相关基因在土拉弗朗西斯菌LVS感染或未感染J774A.;1鼠巨噬细胞中的表达。
- The study about iron metabolism had maken a great breakthrough,and the dependability beteen bone metabolism and iron metabolism is also attracting more attention. 自2001年发现铁调素之后,铁代谢的研究取得了突破性进展,骨代谢与铁代谢相关性的研究也随之引起了越来越多的关注。
- A hereditary disorder affecting iron metabolism in which excessive amounts of iron accumulate in the body tissues.The disorder is characterized by diabetes mellitus, liver dysfunction, and a bronze pigmentation of the skin. 血色素沉着(症),血色病一种影响铁的新陈代谢的遗传性疾病,大量多余的铁淤积在体内组织中。此疾病的特征是糖尿
- Understanding the mechanism of iron metabolism and accurately assessing iron status is important in taking care of the dialysis patient who potentially has the problem of iron deficiency. 摘要本文主旨乃为说明铁的代谢与铁质监测的方式,同时陈述透析患者发生铁质缺乏的原因,与补充铁剂的注意事项并针对使用后衍生之副作用提供护理措施与卫教。
- That maths exam I took was a regular brain drain. 绞尽脑汁的数学测验,我真是绞尽了脑汁。